Lunasin, soluble protein concentration and profile in Glycine soja compared to Glycine max, bioaccessibility and peptides bioactivity
Document Type
Article
Publication Date
2025
Abstract
Lunasin has a wide range of potential health benefits, mostly reported in Glycine max (G. max). Our objective was to compare lunasin and soluble protein concentrations in Glycine soja (G. soja) and G. max, the bioaccessibility of lunasin after digestion, and the bioactivity, in silico, of the peptides produced. Soluble protein concentration extracted from 88 different G. soja accessions had an average of 348.4 ± 77.7 mg/g, while in G. max of 336.2 ± 153.9 mg/g. Some accessions had significant differences in β-conglycinin. Most G. soja accessions had lunasin concentrations between 20 and 25 mg/g defatted flour (DF), while most G. max accessions had lunasin concentrations between 20 and 30 mg/g DF Sequenced peptides EY, EF, ALGLN, GAR, LTEFL, TLEFL, EQAQER, CCDY, DLKAG, EYK and ELLE inhibit angiotensin-converting enzyme, renin, dipeptidyl peptidase-IV and had hypolipidemic and radical scavenger capacities reported in silico. G. soja digests had higher antioxidant (91 % vs. 77 %) and antidiabetic (68 % vs. 25 %) potential compared to G. max digests. © 2025 Elsevier B.V., All rights reserved.
Recommended Citation
Kusumah, Jennifer; Aguado-Preciado, Javier; Yuan, Jiazheng; and Gonzalez de Mejia, Elvira, "Lunasin, soluble protein concentration and profile in Glycine soja compared to Glycine max, bioaccessibility and peptides bioactivity" (2025). College of Health, Science, and Technology. 1149.
https://digitalcommons.uncfsu.edu/college_health_science_technology/1149