Coming of age of long term potentiation: Synaptic plasticity and Alzheimer disease

Document Type

Article

Publication Date

1-1-2011

Abstract

Long term potentiation (LTP) is considered an index of synaptic plasticity. It has been recently demonstrated in humans using non-invasive techniques. At the same time, Alzheimer's disease has been seen as a synaptic failure, but the new diagnostic criteria do not include any psychophysiological measure. Considering that the new criteria exclude patients that do not show memory deterioration, it may be useful to utilize an index of synaptic plasticity in order to improve the chances of early detection. © 2010 Sociedad Neurológica Argentina. Published by Elsevier España, S.L. All rights reserved.

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